Publications
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Adams, R. A., Fernandes-Cerqueira, C., Notarnicola, A., Mertsching, E., Xu, Z. , Lo, W. , Ogilvie, K., Chiang, K. P., Ampudia, J., Rosengren, S., Cubitt, A., King, D. J., Mendlein, J. D., Yang, X., Nangle, L. A., Lundberg, I. E., Jakobsson, P., Schimmel, P. (2019). Serum-circulating His-tRNA synthetase inhibits organ-targeted immune responses. Cellular and Molecular Immunology. doi:10.1038/s41423-019-0331-0 |
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Xu, Z., Lo, W., Beck, D., Schuch, L., Oláhová, M., Kopajtich, R., Chong, Y., Alston, C., Seidl, E., Zhai, L., Lau, C., Timchak, D., LeDuc, C., Borczuk, A., Teich, A., Juusola, J., Sofeso, C., Müller, C., Pierre, G., Hilliard, T., Turnpenny, P., Wagner, M., Kappler, M., Brasch, F., Bouffard, J., Nangle, L., Yang, X., Zhang, M., Taylor, R., Prokisch, H., Griese, M., Chung, W. and Schimmel, P. (2018). Bi-allelic Mutations in Phe-tRNA Synthetase Associated with a Multi-system Pulmonary Disease Support Non-translational Function. The American Journal of Human Genetics, 103(1), pp.100-114. |
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Wei, Z., Xu, Z., Liu, X., Lo, W., Ye, F., Lau, C., Wang, F., Zhou, J., Nangle, L., Yang, X., Zhang, M. and Schimmel, P. (2016). Alternative Splicing Creates Two New Architectures for Human Tyrosyl-tRNA Synthetase. Nucleic Acids Research, 44(3), pp.1247-1255. doi:10.1093/nar/gkw002 |
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Zhou, J. J., Wang, F., Xu, Z. W., Lo, W. S., Lau, C. F., Chinag, K. P., Nangle, L. A., Ashlock, M. A., Mendlein, J. D., Yang, X. L., Zhang, M. J., & Schimmel, P. (2014). Secreted histidyl-trna synthetase splice variants elaborate major epitopes for autoantibodies in inflammatory myositis. The Journal of Biological Chemistry, 289(28), 19269-19275. doi:10.1074/jbc.C114.571026 |
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Lo, W. S., Gardiner, E., Xu, Z. W., Lau, C. F., Wang, F., Zhou, J. J., Mendlein, J. D., Nangle, L. A., Chiang, K. P., Yang, X. L., Au, K. F., Wong, W. H., Guo, M., Zhang, M. J., & Schimmel, P. (2014). Human tRNA synthetase atalytic nulls with diverse functions. Science, 345(6194), 328-332.doi:10.1126/science.1252943 |
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Wang, F. , Xu, Z. W. , Zhou, J., Lo, W. S., Lau, C. F., Nangle, L. A., Yang, X. L., Zhang, M. J., & Schimmel, P. (2013). Regulated capture by exosomes of mRNAs for cytoplasmic tRNA synthetases. The Journal of Biological Chemistry, 288(41), 29223-29228. doi:10.1074/jbc.C113.490599 |
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Xu, Z. W., Wei, Z. Y., Zhou, J. J., Ye, F., Lo, W. S. ,Wang, F. , Lau, C. F., Wu, J. J., Nangie, L. A., Chiang, K. P., Yang, X. L., Zhang, M. J., & Schimmel, P. (2012). Internally deleted human tRNA synthetase suggests evolutionary pressure for repurposing. Structure, 20(9), 1470-1477. doi:10.1016/j.str.2012.08.001 |
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