DNA recombination is the exchange of DNA strands to produce new nucleotide sequence arrangements. Recombination occurs typically, though not exclusively, between regions of similar sequence by breaking and rejoining DNA segments, and is essential for generating genetic diversity and for maintaining genome integrity. It is the basic principle for gene editing with engineered nucleases such as CRISPR and TALEN.
Speakers
R. Daniel CAMERINI-OTERO
National Institutes of Health, US
Dieter EGLI
Columbia University Irving Medical Center
Michael HUEN
The University of Hong Kong
Scott KEENEY
Howard Hughes Medical Institute; Memorial Sloan Kettering Cancer Center
Pei Xin LIM
Memorial Sloan Kettering Cancer Center
Rodney ROTHSTEIN
Columbia University Irving Medical Center
Schedule
09:00 - 09:35
"Poetry in Motion: Increased Chromosomal Mobility after DNA Damage"
Rodney ROTHSTEIN (Columbia University Irving Medical Center)
09:35 - 10:05
"Double Strand Break Repair in the Human Preimplantation Embryo"
Dieter EGLI (Columbia University Irving Medical Center)
10:05 - 10:25
"Consequences of Monoallelic Mutation of Recombination Genes"
Pei Xin LIM (Memorial Sloan Kettering Cancer Center)
10:25 - 10:55
Group Photo Taking and Coffee Break
10:55 - 11:25
"Ensuring Sex Chromosome Recombination in Mouse Meiosis"
Scott KEENEY (Howard Hughes Medical Institute; Memorial Sloan Kettering Cancer Center)
11:25 - 11:55
"The Interplay Between Meiotic Replication and Recombination in Mice and Humans"
R. Daniel CAMERINI-OTERO (National Institutes of Health, US)
11:55 - 12:15
"Coordinating DNA Double-Strand Break Repair with Transcription"
Michael HUEN (The University of Hong Kong)
