Four dimensional conformal field theories (4D CFTs) have a scale anomaly characterized by the coefficient c, which appears as the coefficient of logarithmic terms in momentum space correlation functions of the energy-momentum tensor. By studying the CFT contribution to 4-point graviton scattering amplitudes in Minkowski space, the speaker derives a sum rule for c in terms of TTO operator product expansion (OPE) coefficients, where O is any operator in the theory. The sum rule can be thought of as a version of the optical theorem, and its validity depends on the existence of the massless and forward limits of the correlation functions that contribute. The finiteness of these limits is checked explicitly for free scalar, fermion, and vector CFTs. The sum rule gives c as a sum of positive terms and therefore implies a lower bound on c given any lower bound on TTO OPE coefficients. He computes the coefficients to the sum rule for arbitrary operators of spin 0 and 2, including the energy-momentum tensor.