Overview
DNA recombination is the exchange of DNA strands to produce new nucleotide sequence arrangements. Recombination occurs typically, though not exclusively, between regions of similar sequence by breaking and rejoining DNA segments, and is essential for generating genetic diversity and for maintaining genome integrity. It is the basic principle for gene editing with engineered nucleases such as CRISPR and TALEN.
Speakers
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R. Daniel CAMERINI-OTERO |
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National Institutes of Health, US
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Dieter EGLI |
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Columbia University Irving Medical Center
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Michael HUEN |
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The University of Hong Kong
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Scott KEENEY |
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Howard Hughes Medical Institute; Memorial Sloan Kettering Cancer Center
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Pei Xin LIM |
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Memorial Sloan Kettering Cancer Center
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Rodney ROTHSTEIN |
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Columbia University Irving Medical Center |
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Schedule
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09:00 - 09:35 |
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"Poetry in Motion: Increased Chromosomal Mobility after DNA Damage"
Rodney ROTHSTEIN (Columbia University Irving Medical Center)
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09:35 - 10:05 |
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"Double Strand Break Repair in the Human Preimplantation Embryo"
Dieter EGLI (Columbia University Irving Medical Center)
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10:05 - 10:25 |
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"Consequences of Monoallelic Mutation of Recombination Genes"
Pei Xin LIM (Memorial Sloan Kettering Cancer Center)
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10:25 - 10:55 |
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Group Photo Taking and Coffee Break
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10:55 - 11:25 |
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"Ensuring Sex Chromosome Recombination in Mouse Meiosis"
Scott KEENEY (Howard Hughes Medical Institute; Memorial Sloan Kettering Cancer Center)
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11:25 - 11:55 |
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"The Interplay Between Meiotic Replication and Recombination in Mice and Humans"
R. Daniel CAMERINI-OTERO (National Institutes of Health, US)
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11:55 - 12:15 |
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"Coordinating DNA Double-Strand Break Repair with Transcription"
Michael HUEN (The University of Hong Kong) |
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Organizers
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Maria JASIN (Honorary) |
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Memorial Sloan Kettering Cancer Center
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Bik-Kwoon TYE |
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HKUST (IAS Senior Member) |
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For attendees’ attention
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Seating is on a first come, first served basis. |
HKUST Jockey Club Institute for Advanced Study
Enquiries: ias@ust.hk / 2358 5912
http://ias.ust.hk
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