Abstract
The Golgi is an essential cellular membrane organelle with a unique stacked structure and broad functions in protein and lipid trafficking, processing and secretion. But its structural-functional relationship remains largely unknown. The speaker aims to understand how this stacked structure is formed, why this structure is important for Golgi to function, and how a new Golgi is generated when a cell divides. Most recently, he has gathered intriguing preliminary data concerning Golgi defects in human disorders such as Alzheimer’s diseases and cancer.
About the speaker
Prof Yanzhuang Wang received his BS in zoology in 1987 and MS in cell biology from Nankai University in 1990. He then earned his PhD in molecular cell biology and neurobiology from Heidelberg University in 1999. He started his research career at Yale University in 1999 as a Postdoctoral Associate and became an Associate Research Scientist in 2003. In 2005, he joined the University of Michigan as an Assistant Professor and was promoted to Associate Professor of Molecular, Cellular and Developmental Biology (MCDB) in 2011. He is currently the Professor of MCDB and Neurology.
Prof Wang’s research focuses on the molecular mechanisms of Golgi biogenesis, function and defects in diseases. Recently, he has gathered intriguing preliminary data concerning Golgi defects in human disorders such as Alzheimer’s diseases and cancer. He currently serves on the editorial boards of the World Journal of Biological Chemistry, F1000 Research and the Journal of Biological Chemistry.
Prof Wang is currently a member of the American Society of Cell Biology, the Society of Chinese Bioscientists in America, the American Association for Cancer Research and the American Society for Biochemistry and Molecular Biology. Besides, he was awarded a research grant from Mizutani Foundation for Glycoscience (2014-2015) and the Research Scholar Grant from the American Cancer Society (2009-2014).
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