Schedule
(Updated as of June 11, 2025)
Important notes:
| 1. | This symposium will be held in face-to-face mode. |
| 2. | Unauthorized recording of any session is prohibited. |
| 3. | Please obtain the consent from the speaker concerned for any adaptation/sharing of his/her presentation materials. |
| Should you have further enquiries, please feel free to contact the secretariat by email at ias2025bcem@ust.hk. | |
Venue: Kaisa Group Lecture Theater (IAS LT), G/F, Lo Ka Chung Building, Lee Shau Kee Campus, HKUST
June 9, 2025 (Mon)
Time
Event
| 09:00 - 09:15 |
Registration |
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Session 1 Session Chair: Yuanliang ZHAI (HKUST) |
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| 09:15 - 09:30 |
Opening Remarks Che-ting CHAN (Interim Director, HKUST IAS) and Guojun BU (Head of Life Science, HKUST) |
|
| 09:30 - 10:00 |
#01: Correlative In Situ Structural Biology of Virus Infection Peijun ZHANG (University of Oxford) |
|
| 10:00 - 10:30 |
#02: Chaperonin TRiC Bridges Radial Spokes for Folding Proteins Locally Translated in Mammalian Sperm Flagella Yao CONG (Institute of Biochemistry and Cell Biology, SIBS, Chinese Academy of Sciences) |
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| 10:30 - 10:50 | Coffee Break and Group-photo Taking (Lobby, G/F) | |
| 10:50 - 11:20 |
#03: FIB-based Sample Preparation for Cryo-ET In Situ Structural Biology Beyond Single Cells Christoph KAISER (Max-Planck Institute of Biochemistry) |
|
| 11:20 - 11:50 |
#04: CoCryoViS: Collaborative Online CryoET Visualization System Ivan VIOLA (King Abdullah University of Science and Technology) |
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| 11:50 - 12:20 |
#05: Structural Basis of BAX Pore Formation Yigong SHI (Westlake University; Tsinghua University) |
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| 12:20 - 14:00 | Lunch (By Invitation; Lunch at the UniQue, Conference Lodge) | |
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Session 2 Session Chair: Nan LIU (The University of Hong Kong) |
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| 14:00 - 14:30 |
#06: Innovation of Cryo-EM Specimen Preparation by Graphene and Other Nanomaterials Hongwei WANG (Tsinghua University) |
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| 14:30 - 15:00 |
#07: Capturing the Native Structure of Membrane Protein Using Vesicles Shangyu DANG (HKUST) |
|
| 15:00 - 15:30 |
#08: Pushing Boundaries: isSPA Enhances In Situ Structure Analysis of Membrane Proteins Xinzheng ZHANG (Institute of Biophysics, Chinese Academy of Sciences) |
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| 15:30 - 16:00 |
#09: Novel Inhibitor Discovery Targeting Lipoprotein Transport in Multidrug-resistant Gram-negative Bacteria Yanyan LI (Southern University of Science and Technology) |
|
| 16:00 - 16:20 | Coffee Break (Lobby, G/F) | |
| 16:20 - 16:50 |
#10: Structure of the II2-III2-IV2 Mitochondrial Supercomplex from a Parasite Reveals a Protein Inhibitor of Complex III Alexey AMUNTS (Max Planck Institute of Molecular Physiology; University of Münster) |
|
| 16:50 - 17:20 |
#11: Mechanistic Understanding of the Role of FtsEX in Bacterial Cell Division Min LUO (National University of Singapore) |
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| 17:20 - 17:50 |
#12: Structural Basis of Specific and Nonspecific ABC Transporters Maofu LIAO (Southern University of Science and Technology) |
|
| 17:50 - 18:20 |
#13: Native NMDA Receptors in the Brain: From Atomic Structure to Synaptic Physiology Shujia ZHU (Southern University of Science and Technology) |
|
| 18:20 - 21:00 | Dinner (By invitation; Dinner at Sai Kung) | |
June 10, 2025 (Tue)
Time
Event
|
Session 3 Session Chair: Xiulian YU (The Hong Kong Polytechnic University) |
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| 09:00 - 09:30 |
#14: Non-Equilibrium Structural Pharmacology of the mu-Opioid Receptor Georgios SKINIOTIS (St Jude Children’s Research Hospital) |
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| 09:30 - 10:00 |
#15: Structure-guided Protein Engineering for Therapeutics Yi MIAO (HKUST) |
|
| 10:00 - 10:30 |
#16: GLUT9: Structural Insights and Functional Roles Beyond Urate Transportation Xiaojing PAN (Shenzhen Medical Academy of Research and Translation (SMART)) |
|
| 10:30 - 11:00 | Coffee Break (Lobby, G/F) | |
| 11:00 - 11:30 |
#17: Biological Condensates Enabling Viral Replication Hong ZHOU (University of California, Los Angeles) |
|
| 11:30 - 12:00 |
#18: Icosahedral Structures of Cyanobacterial Carboxysomes and Viruses Qinglu ZENG (HKUST) |
|
| 12:00 - 12:30 |
#19: Molecular Mechanisms of Chromatin Replication Yuanliang ZHAI (HKUST) |
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| 12:30 - 14:00 | Lunch (By Invitation; Lunch at the UniQue, Conference Lodge) | |
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Session 4 Session Chair: Christoph KAISER (Max-Planck Institute of Biochemistry) |
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| 14:00 - 14:30 |
#20: Dynamic Allostery Drives Integrin Avb8 Mediate L-TGF-b Activation Yifan CHENG (University of California, San Francisco) |
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| 14:30 - 15:00 |
#21: Exploring RNA-associated Machines for DNA Manipulation Junjie LIU (Tsinghua University) |
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| 15:00 - 15:30 |
#22: Mechanistic Insights into Chromatin Modulation by the “Orphan” Remodeler ATRX Yang LIU (The University of Hong Kong) |
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| 15:30 - 16:00 |
#23: Krios 5: High Fidelity Ultra High Resolution CryoTEM for Big Data Generation in Life Science Eric CHEN (ThermoFisher Scientific) |
|
| 16:00 - 16:40 |
Poster Presentations (2-minutes each) |
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| 16:40 - 18:20 | Coffee Break and Poster Session (Lobby, G/F) | |
| 18:20 - 20:00 | Dinner (By Invitation; Dinner at the China Garden, HKUST) | |
June 11, 2025 (Wed)
Time
Event
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Session 5 Session Chair: Min LUO (National University of Singapore) |
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| 09:00 - 09:30 |
#24: Unveiling the Architecture and Function of Plasmodium Perforin-like Protein 2 Xiulian YU (The Hong Kong Polytechnic University) |
|
| 09:30 - 10:00 |
#25: Imaging Bacterial Predation Across Scales – from Grappling Hooks to Canons Gregor WEISS (University of Zürich) |
|
| 10:00 - 10:30 |
#26: Structural Basis of IFT-motor-cargo Interaction and Flagellar Asymmetry Masahide KIKKAWA (The University of Tokyo) |
|
| 10:30 - 10:50 | Coffee Break (Lobby, G/F) | |
| 10:50 - 11:20 |
#27: Tspan7 Stabilizes Tubular Membranes Through Polymerization into a Spiral Scaffold Nan LIU (The University of Hong Kong) |
|
| 11:20 - 11:50 |
#28: HELIS: Accurate Helical Parameter Estimation and In-situ Structures of Helical Assemblies Xueming LI (Tsinghua University) |
|
| 11:50 - 12:20 |
#29: (Cryo)-Electron Tomography Analysis of Vacuole Fission in Developing Pollens of Arabidopsis Thaliana Zizhen LIANG (The Chinese University of Hong Kong) |
|
| 12:20 - 14:00 | Lunch (By Invitation; Lunch at the UniQue, Conference Lodge) | |
June 12, 2025 (Thu)
Time
Event
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Session 6 Session Chair: Xiaojing PAN (Shenzhen Medical Academy of Research and Translation (SMART)) |
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| 09:00 - 09:30 |
#30: Project GEM--De Novo Design of GPCR Exoskeleton Modulator Yan ZHANG (Zhejiang University) |
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| 09:30 - 10:00 |
#31: Mechanistic Insights into Plant Hormone Transport Linfeng SUN (University of Science and Technology of China) |
|
| 10:00 - 10:30 |
#32: Activation and Pharmacology of the Calcium-activated Chloride Channel TMEM16A K M Andy LAM (The University of Hong Kong) |
|
| 10:30 - 10:50 | Coffee Break (Lobby, G/F) | |
| 10:50 - 12:30 |
Selected Poster Presentations (15 minutes each) |
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Cryo-EM Structure of Pipsqueak, a Functional Amyloid Involved in Embryonic Development Pablo Adrian GUILLEN POZA (The University of Hong Kong) |
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DiffFitQ: A Rapid Differentiable Fitting Pipeline for Placing Protein Subunits into Large Cryo-EM Maps Deng LUO (King Abdullah University of Science and Technology) |
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Cryo-EM Structure of TMEM63C Suggests It Functions as a Monomer Yuqi QIN (HKUST) |
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Investigation of Hepatitis C Virus-induced Membrane Rearrangements Ilia SIROTKIN (The University of Hong Kong) |
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Structural Insights and Molecular Mechanism of human Na+/H+ exchanger NHA1 Bingjie TANG (HKUST) |
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Molecular Architecture of Nidovirales Double-membrane Vesicle Pore Complex Wenxin ZHANG (The University of Hong Kong) |
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| 12:30 - 14:00 | Lunch (By Invitation; Lunch at the UniQue, Conference Lodge) | |
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Session 7 Session Chair: Yang LIU (The University of Hong Kong) |
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| 14:00 - 14:30 |
#33: Mechanistic Studies of the Canonical and Non-canonical mTORC1 Pathway Zhicheng CUI (University of California, Berkeley) |
|
| 14:30 - 15:00 |
#34: Structure and Regulatory Mechanism of the Lon Protease Chung-I CHANG (Institute of Biological Chemistry, Academia Sinica) |
|
| 15:00 - 15:30 |
#35: Cryo-EM Structure of the Heteromeric Acetyl-CoA Carboxylase Wilson Chun-yu LAU (The Hong Kong Polytechnic University) |
|
| 15:30 - 16:00 |
#36: CPEB4 Amyloid Filaments in Autism Spectrum Disorder Rubén HERVAS MILLAN (The University of Hong Kong) |
|
| 16:00 - 16:20 | Coffee Break (Lobby, G/F) | |
| 16:20 - 16:50 |
#37: Tubulin Isotypes Can Harness the Mechanosensitivity of the Lattice for Microtubule Luminal Accessibility Shih Chieh TI (The University of Hong Kong) |
|
| 16:50 - 17:20 |
#38: The Interplay of Ligand Recognition, Receptor Activation, and Signaling Regulation at the GPCR Dimer Fei XU (ShanghaiTech University) |
|
| 17:20 - 17:50 |
#39: Molecular Insights into Human DNA Double-Strand Break Repair Shikang LIANG (The University of Hong Kong) |
|
| 17:50 - 18:20 |
#40: Progressive Biogenesis of Basal Bodies and Cilia Qiang GUO (Peking University) |
|
| 18:20 - 20:00 | Dinner (By Invitation; Dinner at the UniBistro, HKUST) | |