Schedule
(Updated as of November 4, 2025)
Important notes:
| 1. | This focused program will be held in face-to-face mode. |
| 2. | Unauthorized recording of any session is prohibited. |
| 3. | Please obtain the consent from the speaker concerned for any adaptation/sharing of his/her presentation materials. |
| Should you have further enquiries, please feel free to contact the secretariat by email at ias2025fcbe@ust.hk. | |
Venue: Kaisa Group Lecture Theater (IAS LT), G/F, Lo Ka Chung Building, Lee Shau Kee Campus, HKUST
November 23, 2025 (Sun)
Time
Event
| 18:30 - 21:00 |
Cocktail Reception (For Speakers & Invited Participants Only; Venue: UniQue, Conference Ledge) |
November 24, 2025 (Mon)
Time
Event
| 09:00 - 09:10 |
Registration |
|
| 09:10 - 09:20 |
Opening Remarks |
|
|
Session I: Chromatin Structure & Remodeling I Session Chair: Danny LEUNG (HKUST) |
||
| 09:20 - 09:50 |
Talk #01: Maintenance of Heterochromatin during DNA Replication Danesh MOAZED (Harvard University) |
|
| 09:50 - 10:20 |
Talk #02: Regulation of Heterochromatin Bing ZHU (Institute of Biophysics, Chinese Academy of Sciences) |
|
| 10:20 - 10:50 |
Coffee Break and Group-photo Taking (Venue: Lobby, G/F) |
|
| 10:50 - 11:20 |
Talk #03: The Role of AATF in X Chromosome Inactivation Kui Ming CHAN (City University of Hong Kong) |
|
| 11:20 - 11:50 |
Talk #04: Chemical Approaches to Decoding Histone Epigenetics Xiang David LI (The University of Hong Kong) |
|
| 11:50 - 12:20 |
Talk #05: H3K27me3 Spreading Organizes Canonical PRC1 Chromatin Architecture to Regulate Developmental Programs Nada JABADO (McGill University) |
|
| 12:20 - 14:00 |
Lunch (For Speakers & Invited Participants Only; Venue: IAS Lounge, 5/F) |
|
|
Session II Chromatin Structure & Remodeling II Session Chair: Keda ZHOU (The University of Hong Kong) |
||
| 14:00 - 14:30 |
Talk #06: Functional Compartmentalization of Human Centromeres Aaron STRAIGHT (Stanford University) |
|
| 14:30 - 15:00 |
Talk #07: Spindle Assembly Checkpoint, Inner Kinetochore and Baf-1 are Required for Prophase Chromosome Relocalization and Protection during Nuclear Rupture Karen Wing Yee YUEN (The University of Hong Kong) |
|
| 15:00 - 15:30 |
Talk #08: Roles of Testis-specific H2B Variants H2BWs in Spermatogenesis Toyotaka ISHIBASHI (HKUST) |
|
| 15:30 - 16:00 |
Coffee break & Poster session (Venue: Lobby, G/F) |
|
| 16:00 - 16:30 |
Talk #09: Mechanistic Insights into Chromatin Modulation by the “Orphan” Remodeler ATRX Yang LIU (The University of Hong Kong) |
|
| 16:30 - 17:00 |
Talk #10: Deciphering the Epigenomic Impacts of Repetitive Elements: How Do Retroviruses Control Our Genes? Danny LEUNG (HKUST) |
|
| 17:00 - 17:30 |
Talk #11: Freezing the Fleeting, Revealing the Mechanism of Chromatin Remodeling Zhucheng CHEN (Tsinghua University) |
|
| 17:30 - 18:00 |
Talk #12: Mechanism of Genome Targeting by the LINE-1 Retrotransposon Ruiming XU (Institute of Biophysics, Chinese Academy of Sciences) |
|
| 18:30 - 21:00 |
Dinner at Sai Kung (For Speakers & Invited Participants Only) |
|
November 25, 2025 (Tue)
Time
Event
|
Session III: Epigenetic Memory during DNA Transaction I Session Chair: Kui Ming CHAN (City University of Hong Kong) |
||
| 09:00 - 09:30 |
Talk #13: Shaping the Dynamic Chromatin Landscape for Gene Expression at Single-molecule Resolution Carl WU (Johns Hopkins University) |
|
| 09:30 - 10:00 |
Talk #14: A CMiDAC Deacylation Complex Pillars an Epigenetic Landscape to Prevent Heart Failure Haitao LI (Tsinghua Unviersity) |
|
| 10:00 - 10:30 |
Talk #15: Aneuploidy in Development and Cancer Hongtao YU (Westlake University) |
|
| 10:30 - 10:50 |
Coffee break (Venue: Lobby, G/F) |
|
| 10:50 - 11:10 |
Talk #16: CK2 mediated H2A.Z phosphorylation specifically regulates origin recognition at G1 phase Haizhen LONG (Shenzhen Bay Laboratory) |
|
| 11:10 - 11:30 |
Talk #17: Multiple Activators Drive CMG Maturation to Initiate DNA Replication in Metazoa Yisui XIA (Shenzhen University) |
|
| 11:30 - 12:00 |
Talk #18: Coordination of Leading-strand DNA Replication by Mrc1 Joseph YEELES (MRC Laboratory of Molecular Biology) |
|
| 12:00 - 12:30 |
Talk #19: Mechanisms of Transcription and Replication through Chromatin Lucas FARNUNG (Harvard University) |
|
| 12:30 - 14:00 |
Lunch (For Speakers & Invited Participants Only; Venue: IAS Lounge, 5/F) |
|
|
Section IV: Epigenetic Memory during DNA Transaction II Session Chair: Xiang David LI (The University of Hong Kong) |
||
| 14:00 - 14:30 |
Talk #20: Coordinating Histone Traffic at the Replication Fork Qing LI (Peking University) |
|
| 14:30 - 15:00 |
Talk #21: Mechanism of Chromatin Assembly during DNA Replication Francesca MATTIROLI (Hubrecht Institute) |
|
| 15:00 - 15:30 |
Talk #22: Molecular Mechanism of Chromatin Replication Yuanliang ZHAI (HKUST) |
|
| 15:30 - 16:00 |
Coffee Break & Poster Session (Venue: Lobby, G/F) |
|
| 16:00 - 16:30 |
Talk #23: Parental Nucleosome Disruption at the Replication Fork Shapes Histone Inheritance Pathway Choice Alessandro COSTA (The Francis Crick Institute) |
|
| 16:30 - 17:00 |
Talk #24: A Mechanism for the Symmetric Distribution of Parental Histones during DNA Replication Bik-kwoon TYE (Cornell University; IAS Senior Visitng Fellow) |
|
| 17:00 - 17:30 |
Talk #25: Structural Studies of Chromatin as a Basis for Epigenetic Regulation Hitoshi KURUMIZAKA (The University of Tokyo) |
|
| 18:00 - 21:00 |
Dinner at Tsim Sha Tsui (For Speakers & Invited Participants Only) |
|
November 26, 2025 (Wed)
Time
Event
|
Section V: Epigenetic inheritance & Diseases Session Chair: Qing LI (Peking University) |
||
| 09:00 - 09:30 |
Talk #26: Robust Regulatory Interplay of Enhancers, Facilitators, and Promoters in a Native Chromatin Context John LIS (Cornell University) |
|
| 09:30 - 10:00 |
Talk #27: Structural Basis of Genome Folding and Its Functions in Gene Regulation and Human Diseases Guohong LI (Wuhan University) |
|
| 10:00 - 10:30 |
Talk #28: Mutational Processes in the Context of Chromatin and Epigenome in Cancer Jason Wing Hon WONG (The University of Hong Kong) |
|
| 10:30 - 11:00 |
Coffee break (Venue: Lobby, G/F) |
|
| 11:00 - 11:30 |
Talk #29: R-loops and TOP1CC Regulate DDR in ecDNA Replication and Maintenance Haiyun GAN (Shenzhen Institutes of Advanced Technology) |
|
| 11:30 - 12:00 |
Talk #30: Epigenetic Regulation of Drug Resistance in Cancer Xiaobing SHI (Van Andel Institute) |
|
| 12:00 - 12:30 |
Talk #31: On Our Recent Studies on Epigenetic Inheritance and Cancer Epigenetics Zhiguo ZHANG (Columbia University) |
|
| 12:30 - 12:40 |
Closing Remarks |
|
| 12:40 - 14:00 |
Lunch (For Speakers & Invited Participants Only; Venue: IAS Lounge, 5/F) |
|
| Social Event & Dinner (For Speakers & Invited Participants Only - Optional) |