PROGRAM PROGRAM
PROGRAM

Schedule

(Update as of September 24, 2024)
Important notes:

1. This Program will be held in face-to-face mode.
2. Unauthorized recording of any session is prohibited.
3. Please obtain the consent from the speaker concerned for any adaptation/sharing of his/her presentation materials.
 
Should you have further enquiries, please feel free to contact the secretariat by email at ias2024mt@ust.hk.
 


 

 

 

Venue: Kaisa Group Lecture Theater (IAS LT), G/F, Lo Ka Chung Building, Lee Shau Kee Campus, HKUST
October 27, 2024 (Sun)
Time
Event
18:00 - 20:00 Welcome Dinner (By Invitation; China Garden)

 

 

October 28, 2024 (Mon)
Time
Event
Session 1: Membrane Trafficking in Organelle Biogenesis, Autophagy and Human Diseases
Session Chairs: Lan WANG (HKUST) / Co-chair: Mo WANG (HKUST)
09:00 - 09:05 Opening Remarks
Yang WANG (Vice-President for Institutional Advancement, HKUST)
09:05 - 09:30 ApoE and ApoE Receptors in Alzheimer’s Disease: Pathogenic Trafficking Events
Guojun BU (HKUST)
09:30 - 09:55 The Mechanism of Migrasome Biogenesis
Li YU (Tsinghua University)
09:55 - 10:20 Targeting Golgi Defects for Treatment of Alzheimer’s Disease
Yanzhuang WANG (Shenzhen Bay Laboratory)
10:20 - 10:45 A Distinctive Non-conventional Autophagy Induced by Oncogenic Ras
Liang GE (Tsinghua University)
10:45 - 11:00 Coffee Break and Poster Session (1/F, Lo Ka Chung Building)
11:00 - 11:15 Biochemical Principles Behind the Long-sought Anion Shunting Conductance in Regulated Secretion Suggest New Therapeutic Insights on Human Diseases
Qiuxing JIANG (Laoshan Laboratory; State University of New York at Buffalo)
11:15 - 11:30 The Late Stages of Autophagy
Yueguang RONG (Huazhong University of Science and Technology)
11:30 - 12:15 Mechanisms of Axon Dysfunction in Lysosome-transport Disorders
Juan BONIFACINO (National Institutes of Health, US)
12:15 - 14:00 Lunch (By Invitation; UniQue, Conference Lodge)
Session 2: Membrane Trafficking in Plants and Animals
Session Chair: Yueguang RONG (Huazhong University of Science and Technology) / Co-chair: Xiaohan LI (University of Dundee)
14:00 - 14:25 Organelle Biogenesis and Function in Plants
Liwen JIANG (The Chinese University of Hong Kong)
14:25 - 14:40 Molecular Characterization of Novel ATG8-interacting Proteins in Plant Autophagy
Xiaohong ZHUANG (The Chinese University of Hong Kong)
14:40 - 14:55 UFMylation Functions in ER-phagy for Regulating Plant Stress Responses
Baiying LI (Hong Kong Baptist University)
14:55 - 15:20 A Distant TANGO1 Family Member Promotes Vitellogenin Export from the ER in C. Elegans
Ho Yi MAK (HKUST)
15:20 - 15:35 ESCRT III Mediates Micrometer-sized Plasma Membrane Damage Repair in C. Elegans Epidermal Cell
Suhong XU (Zhejiang University)
15:35 - 15:50 Ectopic Protein Lysine Methacrylation Contributes to Mitochondrial Defects Caused by Loss of Leigh Syndrome Disease Gene HIBCH or ECHS1
Chao TONG (Zhejiang University)
15:50 - 16:00 Short Poster Presentations (1 – 2 mins each)
16:00 - 17:15 Coffee Break and Poster Session (1/F, Lo Ka Chung Building)
17:15 - 18:00 Cargo Receptors in the ER: From Clotting Factors to Cholesterol Regulation
David GINSBURG (University of Michigan Ann Arbor)
18:00 - 18:30 Short Break / Depart from IAS to Sai Kung (for dinner participants only)
18:30 - 21:00 Dinner (By invitation; Dinner at Sai Kung)

 

 

October 29, 2024 (Tue)
Time
Event
Session 3: Mechanisms Mediating Canonical and Non-canonical Membrane Trafficking I
Session Chair: Suhong XU (Zhejiang University) / Co-chair: Xiao TANG (Anhui Normal University)
09:00 - 09:25 Membrane Biogenesis via Bridge-like Lipid Transport Proteins and Integral Membrane Protein Partners
Karin REINISCH (Yale University)
09:25 - 09:50 Mechanism of Membrane Curvature Generation by Flat Disc-like Complexes of Caveolin
Michael KOZLOV (Tel Aviv University)
09:50 - 10:15 Membrane Trafficking and Transmembrane Signaling
Junjie HU (Institute of Biophysics, CAS)
10:15 - 10:40 Unconventional Wisdom in Vesicle Trafficking
Da JIA (Sichuan University)
10:40 - 11:00 Coffee Break (1/F, Lo Ka Chung Building)
11:00 - 11:15 Protein Translocation in Unconventional Secretion and Pathological Involvement
Min ZHANG (Tsinghua University)
11:15 - 11:30 Intrinsically Disordered Regions in Sec24 Paralogs Tune COPII Vesicle Size and Occupancy
Xiaohan LI (University of Dundee)
11:30 - 12:15 How Proteins Cross Membranes
Tom RAPOPORT (Harvard Medical School)
12:15 - 14:00 Lunch (By invitation; UniQue, Conference Lodge)
Session 4: Mechanisms Mediating Canonical and Non-canonical Membrane Trafficking II
Session Chair: Yan ZHAO (Southern University of Science and Technology) / Co-chair: Shenjie WU (University of California, Berkeley)
14:00 - 14:25 Mechanisms of ER Export by the Conserved Cargo Receptor, SURF4
Liz MILLER (University of Dundee)
14:25 - 14:50 Membrane Trafficking in Cell Cycle Regulation and Cancer
David BANFIELD (HKUST)
14:50 - 15:15 A Ubiquitin Ligase Promotes Endosomal Microautophagy and Rescues CLN4 Pathology in iPSC-derived Neuronal and Drosophila Models
Yihong YE (National Institutes of Health, US)
15:15 - 15:30 Self-Constrained COPII Condensation Controls Lipid Homeostasis
Xiao WANG (Peking University)
15:30 - 15:45 Molecular Mechanism that Mediates the Sorting and Secretion of Sonic Hedgehog
Xiao TANG (Anhui Normal University)
15:45 - 16:00 Short Poster Presentations (1 – 2 mins each)
16:00 - 17:15 Coffee Break and Poster Session (1/F, Lo Ka Chung Building)
17:15 - 18:30 IAS Nobel Lecture: Genes, Cells, and Discovery in Basic Science and Disease [Abstract]
Randy SCHEKMAN (University of California, Berkeley; IAS Senior Visiting Fellow)
18:30 - 21:00 Dinner (By Invitation; Dinner at the Conference Lodge)

 

 

October 30, 2024 (Wed)
Time
Event
Session 5: Membrane Trafficking: New Approaches and Perspectives
Session Chair: Xiaohong ZHUANG (The Chinese University of Hong Kong) / Co-chair: Xiao WANG (Peking University)
09:00 - 09:25 Early Steps in the Formation of Lipid Droplets and Lipoproteins
William PRINZ (UT Southwestern Medical Center)
09:25 - 09:50 Talk title to be confirmed
Robert Qi (HKUST, Guangzhou)
09:50 - 10:05 PISD Acts as a Switch between Lipophagy and Fatty Acid Transfer to Mitochondria
Yan ZHAO (Southern University of Science and Technology)
10:05 - 10:20 Shedding Light on Mitochondria and ER Mechanobiology by Optogenetic Mechanostimulators
Liting DUAN (The Chinese University of Hong Kong)
10:20 - 10:40 Coffee Break and Poster Session (1/F, Lo Ka Chung Building)
10:40 - 10:55 Mechanism of Mitochondrial Membrane-protein Quality Control by ATAD1
Lan WANG (HKUST)
10:55 - 11:10 Unconventional Secretion of Alpha-synuclein in Parkinson’s Disease
Shenjie WU (University of California, Berkeley)
11:10 - 11:35 Moving Lipids across Lipid Membranes: A Matter of Life and Death
Xiao-Wei CHEN (Peking University)
11:35 - 12:00 Investigating Protein Sorting in the Secretory Pathway Using an in Vitro Vesicle Formation Assay
Yusong Guo (HKUST)
12:00 - 12:10 Closing Remarks
Guojun BU (Head of Life Science, HKUST)
12:00 - 13:10 Lunch (By Invitation; UniQue, Conference Lodge)