IAS Focused Program on New Technologies and Translational Applications in Genomics

Program

Venue: IAS Lecture Theater, G/F, Lo Ka Chung Building, Lee Shau Kee Campus, HKUST


Updated as of Nov 1, 2018

Time
Event
12:30 - 14:00
Registration
14:00 - 14:05
Opening Remarks
Yang WANG
The Hong Kong University of Science and Technology
(Dean of Science)
Session I: Diagnostics and Clinical Translation
Chair: Melissa FULLWOOD
Cancer Science Institute of Singapore and Nanyang Technological University
14:05 - 15:00
Keynote Lecture: Circulating DNA: From Biology to Diagnostic Applications
Dennis Y. M. LO
The Chinese University of Hong Kong
15:00 - 15:30
Precision Measurements for Microbiology
Iwijn DE VLAMINCK
Cornell University
15:30 - 15:50
Coffee Break (Venue: IAS Lobby, G/F)
15:50 - 16:20
Mutational Landscape of Secondary Glioblastoma Guides MET-targeted Therapy in Brain Tumor
Jiguang WANG
The Hong Kong University of Science and Technology
16:20 - 16:40
Short Talk #1: SplitFusion: An Ultra-sensitive and Fast Method for Detecting Gene Fusions (Abstract)
Baifeng ZHANG
Karolinska Institutet

Short Talk #2: Exploring the Use of Circulating Cell-free RNA in Monitoring Metabolic Diseases (Abstract)
Lian Chye Winston KOH
Agency for Science, Technology and Research
16:40 - 17:10
Novel Precision Medicine Models for Prediction of Immunotherapy Outcomes (Abstract)
Min-Han TAN
Lucence Diagnostics Pte Ltd and Agency for Science, Technology and Research
18:00 - 21:30
Dinner (By Invitation Only; Venue: Wan Chai)
*Coach departs from the IAS at 18:00 and returns at 21:30
Time
Event
Session II: Cancer Genomics
Chair: Yingying WEI
The Chinese University of Hong Kong
09:30 - 10:00
Repression of Human and Mouse Brain Inflammaging Transcriptome by Broad Gene Body Histone Hyperacetylation
Jing-Dong J. HAN
CAS-MPG Partner Institute for Computational Biology
Chinese Academy of Sciences
10:00 - 10:20
Short Talk #03: Pan-cancer Discriminative Genomic Features Predict Histologically Unknown Tissue Origin of Metastatic Tumors (Abstract)
Biaobin JIANG
The Hong Kong University of Science and Technology
(IAS Postdoctoral Fellow)

Short Talk #04: Microfluidics-based 3D Microtumours (3D-MMT) for the Evaluation of Precision Therapies (Abstract)
Shaohua MA
Tsinghua-Berkeley Shenzhen Institute
10:20 - 10:50
Long-read Sequencing Identifies Novel and Tumor-specific Splice Variants in Hepatocellular Carcinoma
Nathalie WONG
The Chinese University of Hong Kong
10:50 - 11:10
Coffee Break (Venue: IAS Lobby, G/F)
11:10 - 11:40
Translating Chromatin Interactions towards the Clinic through Machine Learning and CRISPR-based Methods (Abstract)
Melissa FULLWOOD
Cancer Science Institute of Singapore and Nanyang Technological University
Session III: Computational Genomics
Chair: Jiguang WANG
The Hong Kong University of Science and Technology
11:40 - 12:10
Detection of Cell-type-specific Risk-CpG Sites in Epigenome-wide Association Studies (Abstract)
Yingying WEI
The Chinese University of Hong Kong
12:10 - 14:00
Lunch (Self-arranged)
14:00 - 14:30
Clairvoyante: A Multi-task Convolutional Deep Neural Network for Variant Calling in Single Molecule Sequencing (Abstract)
Ruibang LUO
The University of Hong Kong
14:30 - 15:00
Methods and Applications of Nano-channel-based Optical DNA Mapping (Abstract)
Kevin Yuk-Lap YIP
The Chinese University of Hong Kong
15:00 - 15:30
Group Photo Taking and Coffee Break (Venue: IAS Lobby, G/F)
15:30 - 16:00
Scalable Bioinformatics Methods for Single-cell RNA-seq Analysis (Abstract)
Joshua HO
The University of Hong Kong
16:00 - 16:50
Keynote Lecture: Talk title to be confirmed
Stephen R. QUAKE
Stanford University and Chan Zuckerberg Biohub
18:15 - 20:30
Banquet (By Invitation Only; Venue: Sai Kung)
*Coach departs from the IAS at 18:15 and returns at 20:30
Time
Event
Session IV: Molecular Tools
Chair: Iwijn DE VLAMINCK
Cornell University
09:30 - 10:00
Development and Evaluation of Novel Tools for Genome and Transcriptome Engineering (Abstract)
Meng How TAN
Nanyang Technological University
10:00 - 10:30
DNA-barcoded pMHC Tetramer for Systems Immunology Based Immune Engineering (Abstract)
Ning Jenny JIANG
The University of Texas at Austin
10:30 - 10:50
Coffee Break (Venue: IAS Lobby, G/F)
10:50 - 11:20
Deep Sequencing for Unbiased Genome-wide Profiling of Gene Fusions and CRISPR Targets (Abstract)
Zongli ZHENG
City University of Hong Kong
11:20 - 11:50
A PiggyBac Transposon-based Genetic Screening System in Haploid Human Fungal Pathogen Candida Albicans (Abstract)
Jianbin WANG
Tsinghua University
11:50 - 14:00
Lunch (By Invitation Only; Venue: UniQue, Conference Lodge)
Session V: Devices and Platform Technologies
Chair: Jianbin WANG
Tsinghua University
14:00 - 14:50
Keynote Lecture: Single-cell Analysis with Droplet Microfluidics (Abstract)
David A. WEITZ
Harvard University
14:50 - 15:20
Quantitative Biology with Droplet Microfluidics (Abstract)
Adam ABATE
University of California, San Francisco
15:20 - 15:40
Coffee Break (Venue: IAS Lobby, G/F)
15:40 - 16:10
Error Correction Code Sequencing and Bit Sequencing (Abstract)
Yanyi HUANG
Peking University
16:10 - 16:30
Short Talk #05: Cell Fate Determining Molecular Switches and Signaling Pathway in Pax7-expressing Somitic Mesoderm (Abstract)
Cheuk Wang FUNG
The Hong Kong University of Science and Technology

Short Talk #06: Microfluidic Platform for Bead-based Single Cell Protein Measurement (Abstract)
Sean MICHAEL
The Hong Kong University of Science and Technology
16:30 - 17:00
Imaging and Sequencing Single Cells (Abstract)
Aaron STREETS
University of California, Berkeley
17:00 - 17:05
Closing Remarks
Andrew G. COHEN
The Hong Kong University of Science and Technology
(IAS Director)